Version 5.4
Mus musculus Protein: Itsn1
Summary
InnateDB Protein IDBP-532017.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Itsn1
Protein Name intersectin 1 (SH3 domain protein 1A)
Synonyms AA517634; AA545208; AI316805; AI839402; AI848451; Ehsh1; Ese1; Itsn; Sh3p17;
Species Mus musculus
Ensembl Protein ENSMUSP00000115985
InnateDB Gene IDBG-176668 (Itsn1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 21 experimentally validated interaction(s) in this database.
They are also associated with 99 interaction(s) predicted by orthology.
Experimentally validated
Total 21 [view]
Protein-Protein 21 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 99 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005089 Rho guanyl-nucleotide exchange factor activity
GO:0005515 protein binding
Biological Process
GO:0035023 regulation of Rho protein signal transduction
Cellular Component
Protein Structure and Domains
PDB ID MGI:1338069
InterPro IPR000008 C2 domain
IPR000219 Dbl homology (DH) domain
IPR001849 Pleckstrin homology domain
PFAM PF00168
PF00621
PF00169
PRINTS PR00360
PIRSF
SMART SM00239
SM00325
SM00233
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q80WF1
UniProt Splice Variant
Entrez Gene 16443
UniGene Mm.40546
RefSeq
MGI ID
MGI Symbol Itsn1
OMIM
CCDS
HPRD
IMGT
EMBL AY257970
GenPept AAP13499

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca