InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Trmt2a

Summary

InnateDB Protein

IDBP-532372.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Trmt2a

Protein Name

TRM2 tRNA methyltransferase 2 homolog A (S. cerevisiae)

Synonyms

Htf9c;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000121216

InnateDB Gene

IDBG-141275 (Trmt2a)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Widely expressed at low level. Expressed at higher level in proliferating cells.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 21 interaction(s) predicted by orthology.

Predicted by orthology
Total	21 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003723	RNA binding
GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity
GO:0008168	methyltransferase activity
GO:0008173	RNA methyltransferase activity

Biological Process

GO:0006396	RNA processing
GO:0006464	cellular protein modification process
GO:0032259	methylation

Cellular Component

Protein Structure and Domains

PDB ID

MGI:96270

InterPro

IPR000241 Putative RNA methylase domain
IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase
IPR007848 Methyltransferase small domain
IPR010280 (Uracil-5)-methyltransferase family
IPR029063 S-adenosyl-L-methionine-dependent methyltransferase-like

PFAM

PF01170
PF01135
PF05175
PF05958

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q8BNV1

PhosphoSite