Version 5.4
Mus musculus Protein: Myo5a
Summary
InnateDB Protein IDBP-532417.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Myo5a
Protein Name myosin VA
Synonyms 9630007J19Rik; AI413174; AI661011; d; d-120J; Dbv; flail; flr; MVa; Myo5; MyoVA; Sev-1;
Species Mus musculus
Ensembl Protein ENSMUSP00000121158
InnateDB Gene IDBG-184743 (Myo5a)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 20 experimentally validated interaction(s) in this database.
They are also associated with 22 interaction(s) predicted by orthology.
Experimentally validated
Total 20 [view]
Protein-Protein 20 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 22 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000146 microfilament motor activity
GO:0003774 motor activity
GO:0003779 actin binding
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0005516 calmodulin binding
Biological Process
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0006582 melanin metabolic process
GO:0006887 exocytosis
GO:0007268 synaptic transmission
GO:0007601 visual perception
GO:0030048 actin filament-based movement
GO:0030050 vesicle transport along actin filament
GO:0030073 insulin secretion
GO:0030318 melanocyte differentiation
GO:0031585 regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
GO:0031987 locomotion involved in locomotory behavior
GO:0032252 secretory granule localization
GO:0032400 melanosome localization
GO:0032402 melanosome transport
GO:0042438 melanin biosynthetic process
GO:0042476 odontogenesis
GO:0042552 myelination
GO:0042640 anagen
GO:0042759 long-chain fatty acid biosynthetic process
GO:0043473 pigmentation
GO:0048066 developmental pigmentation
GO:0050808 synapse organization
GO:0051643 endoplasmic reticulum localization
Cellular Component
GO:0001750 photoreceptor outer segment
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005882 intermediate filament
GO:0016459 myosin complex
GO:0030141 secretory granule
GO:0035371 microtubule plus-end
GO:0042470 melanosome
GO:0042641 actomyosin
GO:0043025 neuronal cell body
Protein Structure and Domains
PDB ID MGI:105976
InterPro IPR002710 Dilute
IPR016072 SKP1 component, dimerisation
IPR018444 Dil domain
PFAM PF01466
PF01843
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F6TDE5
UniProt Splice Variant
Entrez Gene 17918
UniGene Mm.419548
RefSeq
MGI ID
MGI Symbol Myo5a
OMIM
CCDS
HPRD
IMGT
EMBL AC133947 CT033761
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca