InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Skil

Summary

InnateDB Protein

IDBP-532643.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Skil

Protein Name

SKI-like

Synonyms

Skir; sno; SnoN;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000123522

InnateDB Gene

IDBG-136318 (Skil)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
They are also associated with 85 interaction(s) predicted by orthology.

Experimentally validated
Total	11 [view]
Protein-Protein	11 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	85 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003682	chromatin binding
GO:0003714	transcription corepressor activity
GO:0005515	protein binding
GO:0019904	protein domain specific binding
GO:0032403	protein complex binding
GO:0046332	SMAD binding

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0001825	blastocyst formation
GO:0002260	lymphocyte homeostasis
GO:0007050	cell cycle arrest
GO:0007179	transforming growth factor beta receptor signaling pathway
GO:0007283	spermatogenesis
GO:0007519	skeletal muscle tissue development
GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway
GO:0034097	response to cytokine
GO:0045596	negative regulation of cell differentiation
GO:0046677	response to antibiotic
GO:0050772	positive regulation of axonogenesis
GO:0070207	protein homotrimerization
GO:0070208	protein heterotrimerization
GO:0070306	lens fiber cell differentiation
GO:1902043	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:1902231	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage

Cellular Component

GO:0001669	acrosomal vesicle
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0016605	PML body
GO:0043234	protein complex

Protein Structure and Domains

PDB ID

MGI:106203

InterPro

IPR003380 Transforming protein Ski
IPR009061 DNA binding domain, putative

PFAM

PF02437

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

D3YYG2

UniProt Splice Variant

Entrez Gene

20482

UniGene

Mm.468161

RefSeq

MGI ID

MGI Symbol

Skil

OMIM

CCDS

HPRD

IMGT

EMBL

AC117590

GenPept