InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Fkbp8

Summary

InnateDB Protein

IDBP-532654.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Fkbp8

Protein Name

FK506 binding protein 8

Synonyms

38kDa; FKBP-38; FKBP-8; Fkbp38;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000118843

InnateDB Gene

IDBG-163357 (Fkbp8)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 71 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	71 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003755	peptidyl-prolyl cis-trans isomerase activity
GO:0005515	protein binding
GO:0005528	FK506 binding

Biological Process

GO:0000413	protein peptidyl-prolyl isomerization
GO:0001708	cell fate specification
GO:0007224	smoothened signaling pathway
GO:0009953	dorsal/ventral pattern formation
GO:0010468	regulation of gene expression
GO:0018208	peptidyl-proline modification
GO:0021904	dorsal/ventral neural tube patterning
GO:0021915	neural tube development
GO:0030510	regulation of BMP signaling pathway
GO:0030513	positive regulation of BMP signaling pathway
GO:0035264	multicellular organism growth
GO:0043010	camera-type eye development
GO:0043066	negative regulation of apoptotic process

Cellular Component

GO:0005739	mitochondrion
GO:0005740	mitochondrial envelope
GO:0030176	integral component of endoplasmic reticulum membrane

Protein Structure and Domains

PDB ID

MGI:1341070

InterPro

IPR001440 Tetratricopeptide TPR1
IPR013026 Tetratricopeptide repeat-containing domain

PFAM

PF00515

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

F6WP10

UniProt Splice Variant

Entrez Gene

14232

UniGene

Mm.453102

RefSeq

MGI ID

MGI Symbol

Fkbp8

OMIM

CCDS

HPRD

IMGT

EMBL

AC157774

GenPept