InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Xpo1

Summary

InnateDB Protein

IDBP-532816.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Xpo1

Protein Name

exportin 1, CRM1 homolog (yeast)

Synonyms

AA420417; Crm1; Exp1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000123634

InnateDB Gene

IDBG-154345 (Xpo1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 20 experimentally validated interaction(s) in this database.
They are also associated with 137 interaction(s) predicted by orthology.

Experimentally validated
Total	20 [view]
Protein-Protein	20 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	137 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005488	binding
GO:0005515	protein binding
GO:0008565	protein transporter activity
GO:0019904	protein domain specific binding

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0006611	protein export from nucleus
GO:0010824	regulation of centrosome duplication
GO:0034504	protein localization to nucleus
GO:0042176	regulation of protein catabolic process
GO:0042493	response to drug
GO:0046825	regulation of protein export from nucleus

Cellular Component

GO:0000776	kinetochore
GO:0005634	nucleus
GO:0005642	annulate lamellae
GO:0030529	ribonucleoprotein complex

Protein Structure and Domains

PDB ID

MGI:2144013

InterPro

IPR016024 Armadillo-type fold

PFAM

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

A2AKT6

UniProt Splice Variant

Entrez Gene

103573

UniGene

RefSeq

MGI ID

MGI Symbol

Xpo1

OMIM

CCDS

HPRD

IMGT

EMBL

AL772359

GenPept