Version 5.4
Mus musculus Protein: Apoc2
Summary
InnateDB Protein IDBP-532974.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Apoc2
Protein Name apolipoprotein C-II
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000118305
InnateDB Gene IDBG-151996 (Apoc2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008047 enzyme activator activity
GO:0008289 lipid binding
GO:0016004 phospholipase activator activity
GO:0042803 protein homodimerization activity
GO:0043274 phospholipase binding
GO:0055102 lipase inhibitor activity
GO:0060230 lipoprotein lipase activator activity
Biological Process
GO:0006629 lipid metabolic process
GO:0006869 lipid transport
GO:0010518 positive regulation of phospholipase activity
GO:0010898 positive regulation of triglyceride catabolic process
GO:0010916 negative regulation of very-low-density lipoprotein particle clearance
GO:0032375 negative regulation of cholesterol transport
GO:0033344 cholesterol efflux
GO:0033700 phospholipid efflux
GO:0034382 chylomicron remnant clearance
GO:0034384 high-density lipoprotein particle clearance
GO:0042493 response to drug
GO:0042953 lipoprotein transport
GO:0043086 negative regulation of catalytic activity
GO:0045723 positive regulation of fatty acid biosynthetic process
GO:0045833 negative regulation of lipid metabolic process
GO:0048261 negative regulation of receptor-mediated endocytosis
GO:0051006 positive regulation of lipoprotein lipase activity
GO:0060697 positive regulation of phospholipid catabolic process
GO:0070328 triglyceride homeostasis
Cellular Component
GO:0034361 very-low-density lipoprotein particle
GO:0034362 low-density lipoprotein particle
GO:0034363 intermediate-density lipoprotein particle
GO:0034366 spherical high-density lipoprotein particle
GO:0042627 chylomicron
Protein Structure and Domains
PDB ID MGI:88054
InterPro IPR008019 Apolipoprotein C-II
PFAM PF05355
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL D3YXE8
UniProt Splice Variant
Entrez Gene 11813
UniGene Mm.483990
RefSeq
MGI ID
MGI Symbol Apoc2
OMIM
CCDS
HPRD
IMGT
EMBL AC149282
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca