InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Rad51

Summary

InnateDB Protein

IDBP-533086.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Rad51

Protein Name

RAD51 homolog (S. cerevisiae)

Synonyms

AV304093; Rad51a; Reca;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000119101

InnateDB Gene

IDBG-198884 (Rad51)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 68 interaction(s) predicted by orthology.

Experimentally validated
Total	13 [view]
Protein-Protein	10 [view]
Protein-DNA	3 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	68 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003677	DNA binding
GO:0003697	single-stranded DNA binding
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0008094	DNA-dependent ATPase activity

Biological Process

GO:0000724	double-strand break repair via homologous recombination
GO:0006200	ATP catabolic process
GO:0006259	DNA metabolic process
GO:0006281	DNA repair
GO:0007126	meiotic nuclear division
GO:0009432	SOS response

Cellular Component

GO:0000793	condensed chromosome
GO:0000794	condensed nuclear chromosome
GO:0000800	lateral element

Protein Structure and Domains

PDB ID

MGI:97890

InterPro

IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical
IPR013632 DNA recombination and repair protein Rad51, C-terminal
IPR013765 DNA recombination and repair protein RecA
IPR020588 DNA recombination and repair protein RecA-like, ATP-binding domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF08423
PF00154

PRINTS

PR00142

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite