InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Krr1

Summary

InnateDB Protein

IDBP-533226.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Krr1

Protein Name

KRR1, small subunit (SSU) processome component, homolog (yeast)

Synonyms

2610511F02Rik; AI255219; AI428520; D10Ertd773e; Hrb2;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000125746

InnateDB Gene

IDBG-190237 (Krr1)

Protein Structure

UniProt Annotation

Function

Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly (By similarity). {ECO:0000250}.

Subcellular Localization

Nucleus, nucleolus {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	14 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003723	RNA binding
GO:0005515	protein binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0006364	rRNA processing
GO:0008150	biological_process

Cellular Component

GO:0005634	nucleus
GO:0005730	nucleolus
GO:0016020	membrane
GO:0030529	ribonucleoprotein complex
GO:0045171	intercellular bridge

Protein Structure and Domains

PDB ID

MGI:1289274

InterPro

IPR004087 K Homology domain
IPR004088 K Homology domain, type 1

PFAM

PF00013
PF13014

PRINTS

PIRSF

SMART

SM00322

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q8BGA5

PhosphoSite

PhosphoSite-

TrEMBL

Q8BVE7

UniProt Splice Variant

Entrez Gene

52705

UniGene

Mm.487426

RefSeq

NP_848725

MGI ID

MGI Symbol

Krr1

OMIM

CCDS

CCDS24168

HPRD

IMGT

EMBL

AC167231 AK030560 AK032472 AK041854 AK078627 AK146926 AK168675 BC089510 BC094236 CH466539

GenPept

AAH89510 AAH94236 BAC27022 BAC27888 BAC31083 BAC37343 BAE27537 BAE40525 EDL21743