Version 5.4
Mus musculus Protein: Sirpa
Summary
InnateDB Protein IDBP-533259.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Sirpa
Protein Name signal-regulatory protein alpha
Synonyms AI835480; Bit; CD172a; P84; Ptpns1; SHP-1; SHPS-1; SIRP;
Species Mus musculus
Ensembl Protein ENSMUSP00000124888
InnateDB Gene IDBG-206000 (Sirpa)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 20 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Experimentally validated
Total 20 [view]
Protein-Protein 18 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0002244 hematopoietic progenitor cell differentiation
GO:0006910 phagocytosis, recognition
GO:0006911 phagocytosis, engulfment
GO:0006928 cellular component movement
GO:0007010 cytoskeleton organization
GO:0007015 actin filament organization
GO:0007160 cell-matrix adhesion
GO:0050766 positive regulation of phagocytosis
Cellular Component
GO:0005887 integral component of plasma membrane
Protein Structure and Domains
PDB ID MGI:108563
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL E0CX65
UniProt Splice Variant
Entrez Gene 19261
UniGene Mm.1682
RefSeq NP_001277951
MGI ID
MGI Symbol Sirpa
OMIM
CCDS
HPRD
IMGT
EMBL AL808126
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca