InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Cbx5

Summary

InnateDB Protein

IDBP-533502.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Cbx5

Protein Name

chromobox homolog 5 (Drosophila HP1a)

Synonyms

2610029O15Rik; C75991; HP1; Hp1a; Hp1alpha;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000120837

InnateDB Gene

IDBG-189469 (Cbx5)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 38 experimentally validated interaction(s) in this database.
They are also associated with 113 interaction(s) predicted by orthology.

Experimentally validated
Total	38 [view]
Protein-Protein	35 [view]
Protein-DNA	3 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	113 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003682	chromatin binding
GO:0005515	protein binding
GO:0035064	methylated histone binding
GO:0042803	protein homodimerization activity
GO:1990226	histone methyltransferase binding

Biological Process

GO:0045892

negative regulation of transcription, DNA-templated

Cellular Component

GO:0000776	kinetochore
GO:0000792	heterochromatin
GO:0005634	nucleus
GO:0005720	nuclear heterochromatin
GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0010369	chromocenter
GO:0016605	PML body

Protein Structure and Domains

PDB ID

MGI:109372

InterPro

IPR000953 Chromo domain/shadow
IPR016197 Chromo domain-like
IPR023780 Chromo domain

PFAM

PF00385

PRINTS

PIRSF

SMART

SM00298

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

D3Z0U2

UniProt Splice Variant

Entrez Gene

12419

UniGene

Mm.473646

RefSeq

MGI ID

MGI Symbol

Cbx5

OMIM

CCDS

HPRD

IMGT

EMBL

AC162693 AC164069

GenPept