InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Mllt4

Summary

InnateDB Protein

IDBP-533654.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Mllt4

Protein Name

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4

Synonyms

5033403D15Rik; Af-6; AF6; Afadin; Gm314; I-afadin; S-afadin;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000114485

InnateDB Gene

IDBG-138450 (Mllt4)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 47 interaction(s) predicted by orthology.

Experimentally validated
Total	7 [view]
Protein-Protein	7 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	47 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0007165

signal transduction

Cellular Component

GO:0005737	cytoplasm
GO:0005911	cell-cell junction
GO:0005912	adherens junction
GO:0005913	cell-cell adherens junction
GO:0030054	cell junction
GO:0045177	apical part of cell

Protein Structure and Domains

PDB ID

MGI:1314653

InterPro

IPR000159 Ras-association
IPR000253 Forkhead-associated (FHA) domain
IPR001478 PDZ domain
IPR002710 Dilute
IPR008984 SMAD/FHA domain
IPR018444 Dil domain
IPR029071 Ubiquitin-related domain

PFAM

PF00788
PF00498
PF00595
PF13180
PF01843

PRINTS

PIRSF

SMART

SM00314
SM00240
SM00228

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite