InnateDB Protein
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IDBP-533657.3
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Hsp90ab1
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Protein Name
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heat shock protein 90 alpha (cytosolic), class B member 1
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Synonyms
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90kDa; AL022974; C81438; Hsp84; Hsp84-1; Hsp90; Hspcb;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000119678
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InnateDB Gene
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IDBG-185482 (Hsp90ab1)
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Protein Structure
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Function |
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Subcellular Localization |
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 72 experimentally validated interaction(s) in this database.
They are also associated with 528 interaction(s) predicted by orthology.
Experimentally validated |
Total |
72
[view]
|
Protein-Protein |
71
[view]
|
Protein-DNA |
1
[view]
|
Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
|
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Predicted by orthology |
Total |
528 [view]
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Molecular Function |
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Biological Process |
GO:0001890
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placenta development
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GO:0006457
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protein folding
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GO:0009651
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response to salt stress
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GO:0032092
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positive regulation of protein binding
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GO:0032435
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negative regulation of proteasomal ubiquitin-dependent protein catabolic process
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GO:0033160
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positive regulation of protein import into nucleus, translocation
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GO:0043524
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negative regulation of neuron apoptotic process
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GO:0045793
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positive regulation of cell size
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GO:0060334
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regulation of interferon-gamma-mediated signaling pathway
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GO:0060338
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regulation of type I interferon-mediated signaling pathway
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GO:0071353
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cellular response to interleukin-4
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GO:0071407
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cellular response to organic cyclic compound
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GO:0071902
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positive regulation of protein serine/threonine kinase activity
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Cellular Component |
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PDB ID |
MGI:96247
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InterPro |
IPR003594
Histidine kinase-like ATPase, ATP-binding domain
IPR020575
Heat shock protein Hsp90, N-terminal
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PFAM |
PF02518
PF13581
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PRINTS |
PR00775
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PIRSF |
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SMART |
SM00387
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TIGRFAMs |
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Modification |
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SwissProt |
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PhosphoSite |
PhosphoSite-
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TrEMBL |
D3Z1R1
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UniProt Splice Variant |
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Entrez Gene |
15516
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UniGene |
Mm.413436
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RefSeq |
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MGI ID |
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MGI Symbol |
Hsp90ab1
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OMIM |
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CCDS |
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HPRD |
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IMGT |
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EMBL |
AC163677
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GenPept |
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