InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Macf1

Summary

InnateDB Protein

IDBP-533822.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Macf1

Protein Name

microtubule-actin crosslinking factor 1

Synonyms

ABP620; Acf7; Aclp7; MACF; mKIAA0465; R74989;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000123246

InnateDB Gene

IDBG-185419 (Macf1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 34 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	34 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003779	actin binding
GO:0003824	catalytic activity
GO:0005515	protein binding
GO:0008017	microtubule binding
GO:0016887	ATPase activity

Biological Process

GO:0001707	mesoderm formation
GO:0006200	ATP catabolic process
GO:0006620	posttranslational protein targeting to membrane
GO:0006928	cellular component movement
GO:0007163	establishment or maintenance of cell polarity
GO:0016055	Wnt signaling pathway
GO:0044237	cellular metabolic process

Cellular Component

GO:0015629	actin cytoskeleton
GO:0015630	microtubule cytoskeleton

Protein Structure and Domains

PDB ID

MGI:108559

InterPro

IPR001715 Calponin homology domain
IPR002017 Spectrin repeat
IPR010997 HRDC-like
IPR018159 Spectrin/alpha-actinin
IPR022613 Calmodulin-regulated spectrin-associated protein, CH domain

PFAM

PF00307
PF00435
PF11971

PRINTS

PIRSF

SMART

SM00033
SM00150

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

Q3UPG9

UniProt Splice Variant

Entrez Gene

11426

UniGene

Mm.487445

RefSeq

MGI ID

MGI Symbol

Macf1

OMIM

CCDS

HPRD

IMGT

EMBL

AK143540 AL606918 AL606932

GenPept

BAE25426