Version 5.4
Mus musculus Protein: Polg
Summary
InnateDB Protein IDBP-534003.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Polg
Protein Name polymerase (DNA directed), gamma
Synonyms AA409516; PolgA;
Species Mus musculus
Ensembl Protein ENSMUSP00000119616
InnateDB Gene IDBG-193972 (Polg)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0004527 exonuclease activity
GO:0005515 protein binding
Biological Process
GO:0006264 mitochondrial DNA replication
GO:0007568 aging
GO:0090305 nucleic acid phosphodiester bond hydrolysis
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005760 gamma DNA polymerase complex
Protein Structure and Domains
PDB ID MGI:1196389
InterPro IPR002297 DNA-directed DNA-polymerase, family A, mitochondria
IPR012337 Ribonuclease H-like domain
PFAM
PRINTS PR00867
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL D6RIP1
UniProt Splice Variant
Entrez Gene 18975
UniGene Mm.487623
RefSeq
MGI ID
MGI Symbol Polg
OMIM
CCDS
HPRD
IMGT
EMBL AC110909
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca