InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ache

Summary

InnateDB Protein

IDBP-534147.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ache

Protein Name

acetylcholinesterase

Synonyms

Species

Mus musculus

Ensembl Protein

ENSMUSP00000117452

InnateDB Gene

IDBG-204838 (Ache)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	7 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003990	acetylcholinesterase activity
GO:0004104	cholinesterase activity
GO:0005518	collagen binding
GO:0017171	serine hydrolase activity
GO:0042803	protein homodimerization activity
GO:0043236	laminin binding
GO:0043621	protein self-association
GO:0052689	carboxylic ester hydrolase activity

Biological Process

GO:0001919	regulation of receptor recycling
GO:0002076	osteoblast development
GO:0006581	acetylcholine catabolic process
GO:0007271	synaptic transmission, cholinergic
GO:0007416	synapse assembly
GO:0019695	choline metabolic process
GO:0031623	receptor internalization
GO:0045212	neurotransmitter receptor biosynthetic process
GO:0048814	regulation of dendrite morphogenesis
GO:0050770	regulation of axonogenesis
GO:0051262	protein tetramerization
GO:0060041	retina development in camera-type eye

Cellular Component

GO:0005605	basal lamina
GO:0005615	extracellular space
GO:0005788	endoplasmic reticulum lumen
GO:0005794	Golgi apparatus
GO:0005886	plasma membrane
GO:0009986	cell surface
GO:0030424	axon
GO:0030425	dendrite
GO:0031594	neuromuscular junction
GO:0042734	presynaptic membrane
GO:0045202	synapse
GO:0045211	postsynaptic membrane
GO:0048471	perinuclear region of cytoplasm

Protein Structure and Domains

PDB ID

MGI:87876

InterPro

PFAM

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

D3Z064

UniProt Splice Variant

Entrez Gene

11423

UniGene

Mm.489229

RefSeq

MGI ID

MGI Symbol

Ache

OMIM

CCDS

HPRD

IMGT

EMBL

AC243288

GenPept