Version 5.4
Homo sapiens Protein: SLC6A7
Summary
InnateDB Protein IDBP-53416.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC6A7
Protein Name solute carrier family 6 (neurotransmitter transporter, L-proline), member 7
Synonyms PROT;
Species Homo sapiens
Ensembl Protein ENSP00000230671
InnateDB Gene IDBG-53414 (SLC6A7)
Protein Structure
UniProt Annotation
Function Terminates the action of proline by its high affinity sodium-dependent reuptake into presynaptic terminals.
Subcellular Localization Membrane; Multi-pass membrane protein.
Disease Associations
Tissue Specificity Brain.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005328 neurotransmitter:sodium symporter activity
Biological Process
GO:0006810 transport
GO:0006836 neurotransmitter transport
GO:0015824 proline transport
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR000175 Sodium:neurotransmitter symporter
PFAM PF00209
PRINTS PR00176
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q99884
PhosphoSite PhosphoSite-Q99884
TrEMBL
UniProt Splice Variant
Entrez Gene 6534
UniGene Hs.241597
RefSeq NP_055043
HUGO HGNC:11054
OMIM 606205
CCDS CCDS4305
HPRD 09371
IMGT
EMBL AC005895 BC069631 BC093785 BC113425 S80071
GenPept AAB47007 AAH69631 AAH93785 AAI13426

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca