Homo sapiens Gene: SLC6A7
Summary
InnateDB Gene IDBG-53414.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC6A7
Gene Name solute carrier family 6 (neurotransmitter transporter, L-proline), member 7
Synonyms PROT
Species Homo sapiens
Ensembl Gene ENSG00000011083
Encoded Proteins
solute carrier family 6 (neurotransmitter transporter, L-proline), member 7
solute carrier family 6 (neurotransmitter transporter, L-proline), member 7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene is a member of the gamma-aminobutyric acid (GABA) neurotransmitter gene family and encodes a high-affinity mammalian brain L-proline transporter protein. This transporter protein differs from other sodium-dependent plasma membrane carriers by its pharmacological specificity, kinetic properties, and ionic requirements. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:150189957-150222788
Strand Forward strand
Band q32
Transcripts
ENST00000230671 ENSP00000230671
ENST00000524041 ENSP00000428200
ENST00000513403
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005328 neurotransmitter:sodium symporter activity
Biological Process
GO:0006810 transport
GO:0006836 neurotransmitter transport
GO:0015824 proline transport
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Na+/Cl- dependent neurotransmitter transporters pathway
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds pathway
Creatine metabolism pathway
Transmembrane transport of small molecules pathway
Metabolism of amino acids and derivatives pathway
Metabolism pathway
SLC-mediated transmembrane transport pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.241597
RefSeq NM_014228
HUGO
OMIM
CCDS CCDS4305
HPRD 09371
IMGT
EMBL
GenPept
RNA Seq Atlas