InnateDB Protein
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IDBP-534357.3
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Fxyd5
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Protein Name
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FXYD domain-containing ion transport regulator 5
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Synonyms
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EF-8; Oit2; RIC;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000125065
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InnateDB Gene
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IDBG-171987 (Fxyd5)
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Protein Structure
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Function |
Involved in down-regulation of E-cadherin which results in reduced cell adhesion. Promotes metastasis (By similarity). {ECO:0000250}.
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Subcellular Localization |
Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
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Disease Associations |
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Tissue Specificity |
Spleen, lung, skeletal muscle, and testis.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
1 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:1201785
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InterPro |
IPR000272
Ion-transport regulator, FXYD motif
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PFAM |
PF02038
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
P97808
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PhosphoSite |
PhosphoSite-P97808
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TrEMBL |
Q3TDW1
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UniProt Splice Variant |
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Entrez Gene |
18301
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UniGene |
Mm.488048
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RefSeq |
XP_006539682
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MGI ID |
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MGI Symbol |
Fxyd5
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OMIM |
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CCDS |
CCDS21121
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HPRD |
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IMGT |
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EMBL |
AK003068
AK155763
AK169966
AK170810
CH466593
U72680
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GenPept |
AAB51040
BAB22545
BAE33425
BAE41487
BAE42043
EDL23968
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