InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ikbkg

Summary

InnateDB Protein

IDBP-534366.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ikbkg

Protein Name

inhibitor of kappaB kinase gamma

Synonyms

1110037D23Rik; AI848108; AI851264; AW124339; IKK[g]; NEMO;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000118884

InnateDB Gene

IDBG-156458 (Ikbkg)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 95 experimentally validated interaction(s) in this database.
They are also associated with 356 interaction(s) predicted by orthology.

Experimentally validated
Total	95 [view]
Protein-Protein	95 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	356 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0019904	protein domain specific binding
GO:0042803	protein homodimerization activity
GO:0046982	protein heterodimerization activity

Biological Process

GO:0001782	B cell homeostasis
GO:0006974	cellular response to DNA damage stimulus
GO:0007250	activation of NF-kappaB-inducing kinase activity
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0051092	positive regulation of NF-kappaB transcription factor activity

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0008385	IkappaB kinase complex

Protein Structure and Domains

PDB ID

MGI:1338074

InterPro

IPR021063 NF-kappa-B essential modulator NEMO, N-terminal

PFAM

PF11577

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

A3KG39

UniProt Splice Variant

Entrez Gene

16151

UniGene

Mm.12967

RefSeq

MGI ID

MGI Symbol

Ikbkg

OMIM

CCDS

HPRD

IMGT

EMBL

AL669976 AL807376

GenPept