InnateDB Protein
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IDBP-534672.4
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Nr6a1
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Protein Name
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nuclear receptor subfamily 6, group A, member 1
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Synonyms
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1700113M01Rik; Gcnf; NCNF; RTR;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000121234
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InnateDB Gene
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IDBG-166859 (Nr6a1)
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Protein Structure
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Function |
Orphan nuclear receptor. Binds to a response element containing the sequence 5'-TCAAGGTCA-3'. May be involved in the regulation of gene expression in germ cell development during gametogenesis. {ECO:0000269PubMed:7854358}.
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Subcellular Localization |
Nucleus {ECO:0000305}.
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Disease Associations |
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Tissue Specificity |
Expressed in the germ cells of both the adult testis and ovary, being most abundant in spermatids. {ECO:0000269PubMed:7835709, ECO:0000269PubMed:7854358}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated |
Total |
8
[view]
|
Protein-Protein |
7
[view]
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Protein-DNA |
1
[view]
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
2 [view]
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|
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Molecular Function |
Accession |
GO Term |
GO:0003700
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sequence-specific DNA binding transcription factor activity
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GO:0003707
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steroid hormone receptor activity
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GO:0008270
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zinc ion binding
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GO:0043565
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sequence-specific DNA binding
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Biological Process |
GO:0006355
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regulation of transcription, DNA-templated
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GO:0043401
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steroid hormone mediated signaling pathway
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Cellular Component |
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PDB ID |
MGI:1352459
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InterPro |
IPR001628
Zinc finger, nuclear hormone receptor-type
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PFAM |
PF00105
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PRINTS |
PR00047
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PIRSF |
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SMART |
SM00399
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TIGRFAMs |
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Modification |
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SwissProt |
|
PhosphoSite |
PhosphoSite-
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TrEMBL |
Z4YMW4
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UniProt Splice Variant |
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Entrez Gene |
14536
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UniGene |
Mm.439703
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RefSeq |
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MGI ID |
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MGI Symbol |
Nr6a1
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OMIM |
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CCDS |
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HPRD |
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IMGT |
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EMBL |
AL844842
AL935155
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GenPept |
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