InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Smarca1

Summary

InnateDB Protein

IDBP-534744.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Smarca1

Protein Name

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1

Synonyms

5730494M04Rik; Snf2l;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000114296

InnateDB Gene

IDBG-142130 (Smarca1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 17 interaction(s) predicted by orthology.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	17 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003676	nucleic acid binding
GO:0003677	DNA binding
GO:0004386	helicase activity
GO:0005524	ATP binding
GO:0016787	hydrolase activity

Biological Process

GO:0006355	regulation of transcription, DNA-templated
GO:0007420	brain development
GO:0008152	metabolic process
GO:2000177	regulation of neural precursor cell proliferation

Cellular Component

GO:0000790

nuclear chromatin

Protein Structure and Domains

PDB ID

MGI:1935127

InterPro

IPR000330 SNF2-related
IPR001650 Helicase, C-terminal
IPR006935 Helicase/UvrB domain
IPR011545 DNA/RNA helicase, DEAD/DEAH box type, N-terminal
IPR014001 Helicase, superfamily 1/2, ATP-binding domain
IPR021006 Histone deacetylase complex, subunit 2/3
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00176
PF00271
PF04851
PF00270
PF11496

PRINTS

PIRSF

SMART

SM00490
SM00487

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite