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InnateDB Protein
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IDBP-534888.4
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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St6galnac6
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Protein Name
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ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
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Synonyms
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Siat7f; ST6GalNAcVI;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000121833
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InnateDB Gene
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IDBG-160625 (St6galnac6)
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Protein Structure
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| Function |
Alpha-2,6-sialyltransferase involved in the synthesis of alpha-series gangliosides. Has activity toward GD1a, GT1b and GM1b. Has no activity toward glycoproteins. Responsible for the biosynthesis of DSGG (disialylgalactosylgloboside) from MSGG (monosialylgalactosylgloboside) in kidney. {ECO:0000269PubMed:10702226}.
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| Subcellular Localization |
Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
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| Disease Associations |
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| Tissue Specificity |
Widely expressed. {ECO:0000269PubMed:10702226}.
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| Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
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| Predicted by orthology |
| Total |
2 [view]
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| PDB ID |
MGI:1355316
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| InterPro |
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| PFAM |
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| PRINTS |
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| PIRSF |
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| SMART |
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| TIGRFAMs |
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| Modification |
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| SwissProt |
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| PhosphoSite |
PhosphoSite-Q9JM95
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| TrEMBL |
Z4YN31
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| UniProt Splice Variant |
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| Entrez Gene |
50935
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| UniGene |
Mm.88831
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| RefSeq |
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| MGI ID |
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| MGI Symbol |
St6galnac6
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| OMIM |
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| CCDS |
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| HPRD |
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| IMGT |
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| EMBL |
AL772271
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| GenPept |
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Version 5.4