Version 5.4
Mus musculus Gene: St6galnac6
Summary
InnateDB Gene IDBG-160625.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol St6galnac6
Gene Name ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
Synonyms Siat7f; ST6GalNAcVI
Species Mus musculus
Ensembl Gene ENSMUSG00000026811
Encoded Proteins
IDBP-160631
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
IDBP-160633
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
IDBP-160635
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
IDBP-160637
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
IDBP-254209
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
IDBP-254211
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
IDBP-538872
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
IDBP-533276
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
IDBP-534888
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
IDBP-532570
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
IDBP-787719
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000160408:
ST6GALNAC6 belongs to a family of sialyltransferases that modify proteins and ceramides on the cell surface to alter cell-cell or cell-extracellular matrix interactions (Tsuchida et al., 2003 [PubMed 12668675]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:32599709-32620806
Strand Forward strand
Band B
Transcripts
ENSMUST00000095045 ENSMUSP00000092655
ENSMUST00000072111 ENSMUSP00000071983
ENSMUST00000095044 ENSMUSP00000092654
ENSMUST00000081879 ENSMUSP00000080555
ENSMUST00000113290 ENSMUSP00000108915
ENSMUST00000113289 ENSMUSP00000108914
ENSMUST00000131229 ENSMUSP00000115430
ENSMUST00000140983 ENSMUSP00000114934
ENSMUST00000145782
ENSMUST00000126636
ENSMUST00000149220
ENSMUST00000129165 ENSMUSP00000121833
ENSMUST00000143625
ENSMUST00000128811 ENSMUSP00000118893
ENSMUST00000183538 ENSMUSP00000138916
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity
GO:0008373 sialyltransferase activity
Biological Process
GO:0001574 ganglioside biosynthetic process
GO:0006486 protein glycosylation
GO:0006677 glycosylceramide metabolic process
GO:0009312 oligosaccharide biosynthetic process
GO:0009988 cell-cell recognition
GO:0097503 sialylation
Cellular Component
GO:0000139 Golgi membrane
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000160408
View Gene Order
ENSBTAG00000044129
Not yet available
Pathways
NETPATH
REACTOME
REACT_248642
Synthesis of substrates in N-glycan biosythesis pathway
REACT_262413
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein pathway
REACT_247926
Metabolism of proteins pathway
REACT_236283
Post-translational protein modification pathway
REACT_237472
Asparagine N-linked glycosylation pathway
REACT_202500
Sialic acid metabolism pathway
KEGG
mmu00604
Glycosphingolipid biosynthesis pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_22433
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein pathway
REACT_22426
Asparagine N-linked glycosylation pathway
REACT_22161
Post-translational protein modification pathway
REACT_22387
Synthesis of substrates in N-glycan biosythesis pathway
REACT_200874
Sialic acid metabolism pathway
REACT_17015
Metabolism of proteins pathway
REACT_223866
Asparagine N-linked glycosylation pathway
REACT_213782
Metabolism of proteins pathway
REACT_214405
Post-translational protein modification pathway
REACT_213420
Sialic acid metabolism pathway
REACT_220681
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein pathway
REACT_226954
Synthesis of substrates in N-glycan biosythesis pathway
KEGG
hsa00604
Glycosphingolipid biosynthesis pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL Z4YLA3 Z4YMI1 Z4YN31
UniProt Splice Variant
Entrez Gene 50935
UniGene Mm.394261 Mm.403001 Mm.407226 Mm.441688 Mm.454468 Mm.88831
RefSeq NM_001025310 NM_001025311 NM_001289547 NM_001289548 NM_001289549 NM_016973 XM_006498167 XM_006498168 XM_006498169 XM_006498170 XM_006498172 XM_006498173
OMIM
CCDS CCDS15922 CCDS15923 CCDS38105
HPRD
IMGT
MGI ID MGI:1355316
MGI Symbol St6galnac6
EMBL AL772271
GenPept
RNA Seq Atlas 50935

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca