InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Col2a1

Summary

InnateDB Protein

IDBP-535016.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Col2a1

Protein Name

collagen, type II, alpha 1

Synonyms

Col2; Col2a; Col2a-1; Del1; Dmm; Lpk; M100856; Rgsc856;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000116951

InnateDB Gene

IDBG-179337 (Col2a1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	13 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding

Biological Process

GO:0001502	cartilage condensation
GO:0001894	tissue homeostasis
GO:0001958	endochondral ossification
GO:0002062	chondrocyte differentiation
GO:0003007	heart morphogenesis
GO:0006029	proteoglycan metabolic process
GO:0010468	regulation of gene expression
GO:0030199	collagen fibril organization
GO:0035108	limb morphogenesis
GO:0042472	inner ear morphogenesis
GO:0048705	skeletal system morphogenesis
GO:0048839	inner ear development
GO:0051216	cartilage development
GO:0060021	palate development
GO:0060348	bone development
GO:0060351	cartilage development involved in endochondral bone morphogenesis
GO:0071773	cellular response to BMP stimulus
GO:2001240	negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

Cellular Component

GO:0005581	collagen trimer
GO:0005585	collagen type II
GO:0005604	basement membrane
GO:0005615	extracellular space
GO:0005737	cytoplasm
GO:0031012	extracellular matrix

Protein Structure and Domains

PDB ID

MGI:88452

InterPro

IPR001007 von Willebrand factor, type C

PFAM

PF00093

PRINTS

PIRSF

SMART

SM00214

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

D3Z7T2

UniProt Splice Variant

Entrez Gene

12824

UniGene

Mm.470559

RefSeq

MGI ID

MGI Symbol

Col2a1

OMIM

CCDS

HPRD

IMGT

EMBL

AC113444 AC134554

GenPept