InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Dact1

Summary

InnateDB Protein

IDBP-535048.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Dact1

Protein Name

dapper homolog 1, antagonist of beta-catenin (xenopus)

Synonyms

4921528D17Rik; AI115603; DAPPER; DAPPER1; Frd1; FRODO; Frodo1; MDpr1; MTNG3; THYEX3;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000117169

InnateDB Gene

IDBG-146832 (Dact1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 19 experimentally validated interaction(s) in this database.
They are also associated with 20 interaction(s) predicted by orthology.

Experimentally validated
Total	19 [view]
Protein-Protein	19 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	20 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0008013	beta-catenin binding
GO:0051018	protein kinase A binding

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0001702	gastrulation with mouth forming second
GO:0030177	positive regulation of Wnt signaling pathway
GO:0030178	negative regulation of Wnt signaling pathway
GO:0031647	regulation of protein stability
GO:0035412	regulation of catenin import into nucleus
GO:0035413	positive regulation of catenin import into nucleus
GO:0045600	positive regulation of fat cell differentiation
GO:0045732	positive regulation of protein catabolic process
GO:0046329	negative regulation of JNK cascade
GO:0048598	embryonic morphogenesis
GO:0048813	dendrite morphogenesis
GO:0050808	synapse organization
GO:0090090	negative regulation of canonical Wnt signaling pathway
GO:2000095	regulation of Wnt signaling pathway, planar cell polarity pathway
GO:2000134	negative regulation of G1/S transition of mitotic cell cycle