InnateDB Protein
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IDBP-535190.4
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Cnga1
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Protein Name
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cyclic nucleotide gated channel alpha 1
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Synonyms
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Cncg;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000119886
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InnateDB Gene
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IDBG-169984 (Cnga1)
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Protein Structure
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Function |
Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger. This protein can be activated by cyclic GMP which leads to an opening of the cation channel and thereby causing a depolarization of rod photoreceptors.
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Subcellular Localization |
Membrane; Multi-pass membrane protein.
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Disease Associations |
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Tissue Specificity |
Rod cells in the retina and inner medulla of kidney.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
1 [view]
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Molecular Function |
Accession |
GO Term |
GO:0005222
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intracellular cAMP activated cation channel activity
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GO:0005223
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intracellular cGMP activated cation channel activity
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GO:0005249
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voltage-gated potassium channel activity
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GO:0030553
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cGMP binding
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:88436
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InterPro |
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PFAM |
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
P29974
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PhosphoSite |
PhosphoSite-P29974
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
12788
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UniGene |
Mm.436652
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RefSeq |
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MGI ID |
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MGI Symbol |
Cnga1
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OMIM |
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CCDS |
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HPRD |
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IMGT |
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EMBL |
BC141261
M84742
U19715
U19716
U19717
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GenPept |
AAA37425
AAA85700
AAA85701
AAA85702
AAI41262
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