InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Fhit

Summary

InnateDB Protein

IDBP-535269.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Fhit

Protein Name

fragile histidine triad gene

Synonyms

AW045638; Fra14A2;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000124957

InnateDB Gene

IDBG-132104 (Fhit)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.

Predicted by orthology
Total	13 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0016787	hydrolase activity
GO:0031625	ubiquitin protein ligase binding
GO:0042802	identical protein binding

Biological Process

GO:0006163	purine nucleotide metabolic process
GO:0006260	DNA replication
GO:0032435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator

Cellular Component

GO:0005829	cytosol
GO:0043231	intracellular membrane-bounded organelle

Protein Structure and Domains

PDB ID

MGI:1277947

InterPro

IPR001310 Histidine triad (HIT) protein
IPR011146 HIT-like domain

PFAM

PF01230

PRINTS

PR00332

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

Q91Y56

UniProt Splice Variant

Entrez Gene

14198

UniGene

Mm.441926

RefSeq

MGI ID

MGI Symbol

Fhit

OMIM

CCDS

HPRD

IMGT

EMBL

AC102431 AC105071 AC154197 AC154360 AC154570 AC154708 AC154776 AC158979 AC159306 AH010680 AL589696 CT485999

GenPept

AAK43475