InnateDB Protein
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IDBP-535504.4
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Dao
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Protein Name
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D-amino acid oxidase
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Synonyms
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AI987963; DAAO; DAMOX; Dao-1; Dao1;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000125588
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InnateDB Gene
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IDBG-192025 (Dao)
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Protein Structure
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Function |
Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D- amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids.
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Subcellular Localization |
Peroxisome.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
3 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:94859
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InterPro |
IPR006076
FAD dependent oxidoreductase
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PFAM |
PF01266
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
P18894
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PhosphoSite |
PhosphoSite-P18894
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
13142
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UniGene |
Mm.20115
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RefSeq |
NP_001273325
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MGI ID |
2DXO
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MGI Symbol |
Dao
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OMIM |
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CCDS |
CCDS19557
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HPRD |
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IMGT |
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EMBL |
AK134813
BC018377
D10210
D10211
M32299
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GenPept |
AAA39367
AAH18377
BAA01062
BAA01063
BAE22296
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