InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Arid1a

Summary

InnateDB Protein

IDBP-535598.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Arid1a

Protein Name

AT rich interactive domain 1A (SWI-like)

Synonyms

1110030E03Rik; BAF250a; Osa1; Smarcf1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000122354

InnateDB Gene

IDBG-195347 (Arid1a)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 30 experimentally validated interaction(s) in this database.
They are also associated with 43 interaction(s) predicted by orthology.

Experimentally validated
Total	30 [view]
Protein-Protein	30 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	43 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0005488	binding
GO:0005515	protein binding
GO:0016922	ligand-dependent nuclear receptor binding
GO:0031491	nucleosome binding

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0001843	neural tube closure
GO:0003205	cardiac chamber development
GO:0003408	optic cup formation involved in camera-type eye development
GO:0006325	chromatin organization
GO:0006337	nucleosome disassembly
GO:0030520	intracellular estrogen receptor signaling pathway
GO:0030521	androgen receptor signaling pathway
GO:0030900	forebrain development
GO:0042921	glucocorticoid receptor signaling pathway
GO:0043044	ATP-dependent chromatin remodeling
GO:0045893	positive regulation of transcription, DNA-templated
GO:0060674	placenta blood vessel development

Cellular Component

GO:0000790	nuclear chromatin
GO:0005622	intracellular
GO:0005634	nucleus
GO:0016514	SWI/SNF complex
GO:0090544	BAF-type complex

Protein Structure and Domains

PDB ID

MGI:1935147

InterPro

IPR001606 ARID/BRIGHT DNA-binding domain
IPR016024 Armadillo-type fold
IPR021906 Protein of unknown function DUF3518

PFAM

PF01388
PF12031

PRINTS

PIRSF

SMART

SM00501

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

Q8R024

UniProt Splice Variant

Entrez Gene

93760

UniGene

Mm.473166

RefSeq

XP_006539388

MGI ID

MGI Symbol

Arid1a

OMIM

CCDS

HPRD

IMGT

EMBL

AK048464 BC028548 BX537327 CR751606 CR925752

GenPept

AAH28548 BAC33346