InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ifnar1

Summary

InnateDB Protein

IDBP-535831.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ifnar1

Protein Name

interferon (alpha and beta) receptor 1

Synonyms

CD118; Ifar; Ifnar; Ifrc; Infar;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000120945

InnateDB Gene

IDBG-176038 (Ifnar1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 22 interaction(s) predicted by orthology.

Experimentally validated
Total	8 [view]
Protein-Protein	8 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	22 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004904	interferon receptor activity
GO:0005515	protein binding

Biological Process

GO:0019221	cytokine-mediated signaling pathway
GO:0032729	positive regulation of interferon-gamma production
GO:0042110	T cell activation
GO:0045087	innate immune response (InnateDB)
GO:0045351	type I interferon biosynthetic process
GO:0050718	positive regulation of interleukin-1 beta secretion
GO:0051607	defense response to virus

Cellular Component

Protein Structure and Domains

PDB ID

MGI:107658

InterPro

IPR003961 Fibronectin, type III

PFAM

PF00041
PF01108

PRINTS

PIRSF

SMART

SM00060

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

Q3U5G8

UniProt Splice Variant

Entrez Gene

15975

UniGene

Mm.502

RefSeq

MGI ID

MGI Symbol

Ifnar1

OMIM

CCDS

HPRD

IMGT

EMBL

AC132272 AC150035 AK153583

GenPept

BAE32110