Version 5.4
Mus musculus Protein: Zmiz1
Summary
InnateDB Protein IDBP-535962.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Zmiz1
Protein Name zinc finger, MIZ-type containing 1
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000124863
InnateDB Gene IDBG-138696 (Zmiz1)
Protein Structure
UniProt Annotation
Function Increases ligand-dependent transcriptional activity of AR and promotes AR sumoylation. The stimulation of AR activity is dependent upon sumoylation (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus speckle {ECO:0000250}. Cytoplasm {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008270 zinc ion binding
Biological Process
GO:0001570 vasculogenesis
GO:0001701 in utero embryonic development
GO:0003007 heart morphogenesis
GO:0006351 transcription, DNA-templated
GO:0007296 vitellogenesis
GO:0007569 cell aging
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0048146 positive regulation of fibroblast proliferation
GO:0048589 developmental growth
GO:0048844 artery morphogenesis
Cellular Component
GO:0005737 cytoplasm
GO:0016607 nuclear speck
Protein Structure and Domains
PDB ID MGI:3040693
InterPro IPR004181 Zinc finger, MIZ-type
PFAM PF02891
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6P1E1
PhosphoSite PhosphoSite-Q6P1E1
TrEMBL E0CX95
UniProt Splice Variant
Entrez Gene 328365
UniGene Mm.489608
RefSeq NP_899031
MGI ID
MGI Symbol Zmiz1
OMIM
CCDS CCDS26873
HPRD
IMGT
EMBL AC154455 AC154759 AC157650 AK054366 BC057691 BC058646 BC065120
GenPept AAH57691 AAH58646 AAH65120 BAC35753

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca