InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Mre11a

Summary

InnateDB Protein

IDBP-536211.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Mre11a

Protein Name

meiotic recombination 11 homolog A (S. cerevisiae)

Synonyms

Mre11; Mre11b;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000119999

InnateDB Gene

IDBG-134704 (Mre11a)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 52 interaction(s) predicted by orthology.

Experimentally validated
Total	8 [view]
Protein-Protein	7 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	1 [view]
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	52 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004519	endonuclease activity
GO:0030145	manganese ion binding

Biological Process

GO:0006302

double-strand break repair

Cellular Component

GO:0005634

nucleus

Protein Structure and Domains

PDB ID

MGI:1100512

InterPro

IPR007281 Mre11, DNA-binding

PFAM

PF04152

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

17535

UniGene

Mm.413091

RefSeq

MGI ID

MGI Symbol

Mre11a

OMIM

CCDS

HPRD

IMGT

EMBL

GenPept