InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Lepr

Summary

InnateDB Protein

IDBP-536271.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Lepr

Protein Name

leptin receptor

Synonyms

db; diabetes; Leprb; LEPROT; Modb1; OB-RGRP; obese-like; obl; Obr;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000123654

InnateDB Gene

IDBG-167734 (Lepr)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.

Experimentally validated
Total	13 [view]
Protein-Protein	13 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	16 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004888	transmembrane signaling receptor activity
GO:0005515	protein binding
GO:0042802	identical protein binding

Biological Process

GO:0007165	signal transduction
GO:0008203	cholesterol metabolic process
GO:0019222	regulation of metabolic process
GO:0045721	negative regulation of gluconeogenesis
GO:0051346	negative regulation of hydrolase activity

Cellular Component

GO:0005887	integral component of plasma membrane
GO:0043235	receptor complex

Protein Structure and Domains

PDB ID

MGI:104993

InterPro

PFAM

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

A2AV66

UniProt Splice Variant

Entrez Gene

16847

UniGene

Mm.407284

RefSeq

MGI ID

MGI Symbol

Lepr

OMIM

CCDS

HPRD

IMGT

EMBL

AL929373

GenPept