InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Grb7

Summary

InnateDB Protein

IDBP-536358.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Grb7

Protein Name

growth factor receptor bound protein 7

Synonyms

mKIAA4028;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000119926

InnateDB Gene

IDBG-210622 (Grb7)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 35 interaction(s) predicted by orthology.

Experimentally validated
Total	13 [view]
Protein-Protein	13 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	35 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005070	SH3/SH2 adaptor activity
GO:0019901	protein kinase binding
GO:0035091	phosphatidylinositol binding
GO:0042802	identical protein binding

Biological Process

GO:0007165	signal transduction
GO:0009967	positive regulation of signal transduction
GO:0030335	positive regulation of cell migration

Cellular Component

GO:0005829	cytosol
GO:0005925	focal adhesion

Protein Structure and Domains

PDB ID

MGI:102683

InterPro

IPR000159 Ras-association
IPR029071 Ubiquitin-related domain

PFAM

PF00788

PRINTS

PIRSF

SMART

SM00314

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

A2A555

UniProt Splice Variant

Entrez Gene

14786

UniGene

Mm.276702

RefSeq

MGI ID

MGI Symbol

Grb7

OMIM

CCDS

HPRD

IMGT

EMBL

AL591390

GenPept