Version 5.4
Mus musculus Protein: Socs2
Summary
InnateDB Protein IDBP-536487.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Socs2
Protein Name suppressor of cytokine signaling 2
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000118720
InnateDB Gene IDBG-187117 (Socs2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 16 experimentally validated interaction(s) in this database.
Experimentally validated
Total 16 [view]
Protein-Protein 16 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005131 growth hormone receptor binding
GO:0005159 insulin-like growth factor receptor binding
GO:0005515 protein binding
GO:0008269 JAK pathway signal transduction adaptor activity
Biological Process
GO:0001558 regulation of cell growth
GO:0007595 lactation
GO:0035556 intracellular signal transduction
GO:0040014 regulation of multicellular organism growth
GO:0040015 negative regulation of multicellular organism growth
GO:0045666 positive regulation of neuron differentiation
GO:0046426 negative regulation of JAK-STAT cascade
GO:0060749 mammary gland alveolus development
Cellular Component
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:1201787
InterPro IPR000980 SH2 domain
PFAM PF00017
PF14633
PRINTS PR00401
PIRSF
SMART SM00252
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL D3Z441
UniProt Splice Variant
Entrez Gene 216233
UniGene Mm.474283
RefSeq
MGI ID
MGI Symbol Socs2
OMIM
CCDS
HPRD
IMGT
EMBL AC167222
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca