Version 5.4
Mus musculus Protein: Egr2
Summary
InnateDB Protein IDBP-536619.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Egr2
Protein Name early growth response 2
Synonyms Egr-2; Krox-20; Krox20; NGF1-B; Zfp-25; Zfp-6;
Species Mus musculus
Ensembl Protein ENSMUSP00000116502
InnateDB Gene IDBG-159898 (Egr2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 64 experimentally validated interaction(s) in this database.
They are also associated with 17 interaction(s) predicted by orthology.
Experimentally validated
Total 64 [view]
Protein-Protein 10 [view]
Protein-DNA 53 [view]
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 17 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0031625 ubiquitin protein ligase binding
GO:0071837 HMG box domain binding
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0007611 learning or memory
GO:0007622 rhythmic behavior
GO:0008045 motor neuron axon guidance
GO:0014037 Schwann cell differentiation
GO:0021569 rhombomere 3 development
GO:0021612 facial nerve structural organization
GO:0021660 rhombomere 3 formation
GO:0021666 rhombomere 5 formation
GO:0030278 regulation of ossification
GO:0032868 response to insulin
GO:0035284 brain segmentation
GO:0035914 skeletal muscle cell differentiation
GO:0042552 myelination
GO:0043066 negative regulation of apoptotic process
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0048168 regulation of neuronal synaptic plasticity
GO:0071310 cellular response to organic substance
GO:0071320 cellular response to cAMP
GO:0071371 cellular response to gonadotropin stimulus
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID MGI:95296
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL D3Z4X9
UniProt Splice Variant
Entrez Gene 13654
UniGene Mm.290421
RefSeq
MGI ID
MGI Symbol Egr2
OMIM
CCDS
HPRD
IMGT
EMBL AC153379
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca