InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Tnfrsf9

Summary

InnateDB Protein

IDBP-536744.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Tnfrsf9

Protein Name

tumor necrosis factor receptor superfamily, member 9

Synonyms

4-1BB; A930040I11Rik; AA408498; AI325004; Cd137; CDw137; ILA; Ly63;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000120761

InnateDB Gene

IDBG-205902 (Tnfrsf9)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.

Experimentally validated
Total	12 [view]
Protein-Protein	11 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	8 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004872	receptor activity
GO:0005515	protein binding
GO:0019955	cytokine binding

Biological Process

GO:0042127	regulation of cell proliferation
GO:0045087	innate immune response (InnateDB)
GO:0070207	protein homotrimerization
GO:2001180	negative regulation of interleukin-10 secretion
GO:2001183	negative regulation of interleukin-12 secretion

Cellular Component

GO:0005615	extracellular space
GO:0009897	external side of plasma membrane

Protein Structure and Domains

PDB ID

MGI:1101059

InterPro

IPR001368 TNFR/NGFR cysteine-rich region

PFAM

PF00020

PRINTS

PIRSF

SMART

SM00208

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

A2A887

UniProt Splice Variant

Entrez Gene

21942

UniGene

Mm.416252

RefSeq

MGI ID

MGI Symbol

Tnfrsf9

OMIM

CCDS

HPRD

IMGT

EMBL

AL607084 AL607143

GenPept