Version 5.4
Mus musculus Protein: Nfkb1
Summary
InnateDB Protein IDBP-536783.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Nfkb1
Protein Name nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105
Synonyms NF-kappaB; NF-kappaB1; NF-KB1; p105; p50; p50/p105;
Species Mus musculus
Ensembl Protein ENSMUSP00000114798
InnateDB Gene IDBG-195445 (Nfkb1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 111 experimentally validated interaction(s) in this database.
They are also associated with 209 interaction(s) predicted by orthology.
Experimentally validated
Total 111 [view]
Protein-Protein 41 [view]
Protein-DNA 65 [view]
Protein-RNA 4 [view]
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 209 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0007165 signal transduction
GO:0045087 innate immune response (InnateDB)
Cellular Component
Protein Structure and Domains
PDB ID MGI:97312
InterPro IPR000488 Death domain
IPR002110 Ankyrin repeat
IPR011029 Death-like domain
IPR020683 Ankyrin repeat-containing domain
PFAM PF00531
PF00023
PF13606
PF11929
PF12796
PRINTS PR01415
PIRSF
SMART SM00005
SM00248
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 18033
UniGene
RefSeq
MGI ID
MGI Symbol Nfkb1
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca