Version 5.4
Mus musculus Protein: Eif2b1
Summary
InnateDB Protein IDBP-536798.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Eif2b1
Protein Name eukaryotic translation initiation factor 2B, subunit 1 (alpha)
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000122923
InnateDB Gene IDBG-200814 (Eif2b1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 16 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 16 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005515 protein binding
Biological Process
GO:0006446 regulation of translational initiation
GO:0043087 regulation of GTPase activity
GO:0044237 cellular metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005851 eukaryotic translation initiation factor 2B complex
GO:0005886 plasma membrane
GO:0016020 membrane
Protein Structure and Domains
PDB ID MGI:2384802
InterPro IPR000649 Initiation factor 2B-related
PFAM PF01008
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL D3Z151
UniProt Splice Variant
Entrez Gene 209354
UniGene Mm.420891
RefSeq
MGI ID
MGI Symbol Eif2b1
OMIM
CCDS
HPRD
IMGT
EMBL AC127313
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca