InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Erbb4

Summary

InnateDB Protein

IDBP-536962.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Erbb4

Protein Name

v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)

Synonyms

c-erbB-4; Her4;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000115373

InnateDB Gene

IDBG-164078 (Erbb4)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 51 interaction(s) predicted by orthology.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	51 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004714	transmembrane receptor protein tyrosine kinase activity
GO:0005524	ATP binding
GO:0016772	transferase activity, transferring phosphorus-containing groups

Biological Process

GO:0006468	protein phosphorylation
GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007399	nervous system development
GO:0007507	heart development
GO:0018108	peptidyl-tyrosine phosphorylation
GO:0045165	cell fate commitment

Cellular Component

GO:0016020	membrane
GO:0043235	receptor complex

Protein Structure and Domains

PDB ID

MGI:104771

InterPro

IPR000494 EGF receptor, L domain
IPR006211 Furin-like cysteine-rich domain
IPR006212 Furin-like repeat
IPR009030 Insulin-like growth factor binding protein, N-terminal
IPR011009 Protein kinase-like domain

PFAM

PF01030
PF00757

PRINTS

PIRSF

SMART

SM00261

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite