Version 5.4
Mus musculus Protein: Sparc
Summary
InnateDB Protein IDBP-536988.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Sparc
Protein Name secreted acidic cysteine rich glycoprotein
Synonyms BM-40; ON;
Species Mus musculus
Ensembl Protein ENSMUSP00000119475
InnateDB Gene IDBG-175174 (Sparc)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 20 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.
Experimentally validated
Total 20 [view]
Protein-Protein 18 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 18 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0050840 extracellular matrix binding
Biological Process
GO:0042127 regulation of cell proliferation
GO:0060348 bone development
GO:0071363 cellular response to growth factor stimulus
Cellular Component
GO:0005615 extracellular space
GO:0031012 extracellular matrix
Protein Structure and Domains
PDB ID MGI:98373
InterPro IPR002350 Kazal domain
IPR003645 Follistatin-like, N-terminal
IPR015369 Follistatin/Osteonectin EGF domain
PFAM PF00050
PF07648
PF09289
PRINTS
PIRSF
SMART SM00280
SM00274
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q5NCU3
UniProt Splice Variant
Entrez Gene 20692
UniGene Mm.399793
RefSeq
MGI ID
MGI Symbol Sparc
OMIM
CCDS
HPRD
IMGT
EMBL AL596207 AL772268
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca