Version 5.4
Mus musculus Protein: Ift80
Summary
InnateDB Protein IDBP-536997.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ift80
Protein Name intraflagellar transport 80 homolog (Chlamydomonas)
Synonyms 4921524P20Rik; mKIAA1374; Wdr56;
Species Mus musculus
Ensembl Protein ENSMUSP00000118406
InnateDB Gene IDBG-150941 (Ift80)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0001649 osteoblast differentiation
GO:0002062 chondrocyte differentiation
GO:0007224 smoothened signaling pathway
GO:0042073 intraciliary transport
GO:0042384 cilium assembly
GO:0045880 positive regulation of smoothened signaling pathway
GO:0050680 negative regulation of epithelial cell proliferation
GO:0060271 cilium morphogenesis
GO:0060349 bone morphogenesis
GO:2000051 negative regulation of non-canonical Wnt signaling pathway
Cellular Component
GO:0005813 centrosome
GO:0005929 cilium
GO:0030992 intraciliary transport particle B
GO:0036064 ciliary basal body
Protein Structure and Domains
PDB ID MGI:1915509
InterPro IPR001680 WD40 repeat
IPR017986 WD40-repeat-containing domain
PFAM PF00400
PRINTS
PIRSF
SMART SM00320
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL D3Z157
UniProt Splice Variant
Entrez Gene 68259
UniGene Mm.490774
RefSeq
MGI ID
MGI Symbol Ift80
OMIM
CCDS
HPRD
IMGT
EMBL AC115062 AC122876
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca