InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Penk

Summary

InnateDB Protein

IDBP-537003.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Penk

Protein Name

preproenkephalin

Synonyms

AI326464; ENK; Penk1; PPA;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000122389

InnateDB Gene

IDBG-128498 (Penk)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001515	opioid peptide activity

Biological Process

GO:0001662	behavioral fear response
GO:0001964	startle response
GO:0002118	aggressive behavior
GO:0007218	neuropeptide signaling pathway
GO:0007626	locomotory behavior
GO:0019233	sensory perception of pain

Cellular Component

GO:0005576

extracellular region

Protein Structure and Domains

PDB ID

MGI:104629

InterPro

IPR000703 Proenkephalin A
IPR006024 Opioid neuropeptide precursor

PFAM

PF01160

PRINTS

PR01029
PR01028

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

B1AZQ0

UniProt Splice Variant

Entrez Gene

18619

UniGene

Mm.475097

RefSeq

MGI ID

MGI Symbol

Penk

OMIM

CCDS

HPRD

IMGT

EMBL

AL732517 BX004841

GenPept