Version 5.4
Mus musculus Gene: Penk
Summary
InnateDB Gene IDBG-128498.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Penk
Gene Name preproenkephalin
Synonyms AI326464; ENK; Penk1; PPA
Species Mus musculus
Ensembl Gene ENSMUSG00000045573
Encoded Proteins
IDBP-128500
preproenkephalin
IDBP-537003
preproenkephalin
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000181195:
Gene Information
Type Protein coding
Genomic Location Chromosome 4:4133531-4138819
Strand Reverse strand
Band A1
Transcripts
ENSMUST00000070375 ENSMUSP00000066822
ENSMUST00000133567 ENSMUSP00000122389
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001515 opioid peptide activity
GO:0005515 protein binding
Biological Process
GO:0001662 behavioral fear response
GO:0001964 startle response
GO:0002118 aggressive behavior
GO:0007218 neuropeptide signaling pathway
GO:0007626 locomotory behavior
GO:0019233 sensory perception of pain
Cellular Component
GO:0005576 extracellular region
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000181195
View Gene Order
ENSBTAG00000004924
Not yet available
Pathways
NETPATH
REACTOME
REACT_223625
GPCR downstream signaling pathway
REACT_254215
Signaling by GPCR pathway
REACT_261161
Class A/1 (Rhodopsin-like receptors) pathway
REACT_231468
GPCR ligand binding pathway
REACT_235286
Peptide ligand-binding receptors pathway
REACT_250376
G alpha (i) signalling events pathway
REACT_188257
Signal Transduction pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_19231
G alpha (i) signalling events pathway
REACT_14819
Peptide ligand-binding receptors pathway
REACT_14828
Class A/1 (Rhodopsin-like receptors) pathway
REACT_14797
Signaling by GPCR pathway
REACT_111102
Signal Transduction pathway
REACT_19184
GPCR downstream signaling pathway
REACT_21340
GPCR ligand binding pathway
REACT_219025
Peptide ligand-binding receptors pathway
REACT_205369
Signaling by GPCR pathway
REACT_210568
G alpha (i) signalling events pathway
REACT_214353
Signal Transduction pathway
REACT_214436
GPCR downstream signaling pathway
REACT_220217
GPCR ligand binding pathway
REACT_208412
Class A/1 (Rhodopsin-like receptors) pathway
KEGG
INOH
PID NCI
ap1_pathway
AP-1 transcription factor network
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.475097
RefSeq NM_001002927 XM_006537675
OMIM
CCDS CCDS17946
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca