Version 5.4
Mus musculus Protein: Asns
Summary
InnateDB Protein IDBP-537030.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Asns
Protein Name asparagine synthetase
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000120489
InnateDB Gene IDBG-128303 (Asns)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 25 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 25 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity
GO:0042803 protein homodimerization activity
GO:0048037 cofactor binding
Biological Process
GO:0001889 liver development
GO:0006529 asparagine biosynthetic process
GO:0008152 metabolic process
GO:0009416 response to light stimulus
GO:0009612 response to mechanical stimulus
GO:0009636 response to toxic substance
GO:0031427 response to methotrexate
GO:0032354 response to follicle-stimulating hormone
GO:0032870 cellular response to hormone stimulus
GO:0042149 cellular response to glucose starvation
GO:0043066 negative regulation of apoptotic process
GO:0043200 response to amino acid
GO:0045931 positive regulation of mitotic cell cycle
Cellular Component
Protein Structure and Domains
PDB ID MGI:1350929
InterPro IPR000583 Class II glutamine amidotransferase domain
IPR029055 Nucleophile aminohydrolases, N-terminal
PFAM PF00310
PF13537
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL D3Z028
UniProt Splice Variant
Entrez Gene 27053
UniGene Mm.2942
RefSeq
MGI ID
MGI Symbol Asns
OMIM
CCDS
HPRD
IMGT
EMBL AC129291
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca