InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Asns

Summary

InnateDB Gene

IDBG-128303.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Asns

Gene Name

asparagine synthetase

Synonyms

Species

Mus musculus

Ensembl Gene

ENSMUSG00000029752

Encoded Proteins

IDBP-128305

asparagine synthetase

IDBP-249399

asparagine synthetase

IDBP-540504

asparagine synthetase

IDBP-537030

asparagine synthetase

IDBP-531986

asparagine synthetase

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000070669:
The protein encoded by this gene is involved in the synthesis of asparagine. This gene complements a mutation in the temperature-sensitive hamster mutant ts11, which blocks progression through the G1 phase of the cell cycle at nonpermissive temperature. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, May 2010]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 6:7675169-7693254

Strand

Reverse strand

Band

Transcripts

ENSMUST00000031766	ENSMUSP00000031766
ENSMUST00000115542	ENSMUSP00000111204
ENSMUST00000140097
ENSMUST00000133972
ENSMUST00000126303	ENSMUSP00000115415
ENSMUST00000139596	ENSMUSP00000120489
ENSMUST00000148349	ENSMUSP00000118003

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 25 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	25 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004066	asparagine synthase (glutamine-hydrolyzing) activity
GO:0005524	ATP binding
GO:0042803	protein homodimerization activity
GO:0048037	cofactor binding

Biological Process

GO:0001889	liver development
GO:0006520	cellular amino acid metabolic process
GO:0006529	asparagine biosynthetic process
GO:0006541	glutamine metabolic process
GO:0008152	metabolic process
GO:0009416	response to light stimulus
GO:0009612	response to mechanical stimulus
GO:0009636	response to toxic substance
GO:0031427	response to methotrexate
GO:0031667	response to nutrient levels
GO:0032354	response to follicle-stimulating hormone
GO:0032870	cellular response to hormone stimulus
GO:0042149	cellular response to glucose starvation
GO:0043066	negative regulation of apoptotic process
GO:0043200	response to amino acid
GO:0045931	positive regulation of mitotic cell cycle
GO:0070981	L-asparagine biosynthetic process