InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Adam12

Summary

InnateDB Protein

IDBP-537327.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Adam12

Protein Name

a disintegrin and metallopeptidase domain 12 (meltrin alpha)

Synonyms

mKIAA4001; Mltna;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000120094

InnateDB Gene

IDBG-211287 (Adam12)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Experimentally validated
Total	8 [view]
Protein-Protein	7 [view]
Protein-DNA	0
Protein-RNA	1 [view]
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004222	metalloendopeptidase activity
GO:0008270	zinc ion binding
GO:0017124	SH3 domain binding

Biological Process

GO:0006508

proteolysis

Cellular Component

GO:0005634	nucleus
GO:0005739	mitochondrion
GO:0005886	plasma membrane

Protein Structure and Domains

PDB ID

MGI:105378

InterPro

IPR002870 Peptidase M12B, propeptide

PFAM

PF01562

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

D3YUK3

UniProt Splice Variant

Entrez Gene

11489

UniGene

Mm.439714

RefSeq

MGI ID

MGI Symbol

Adam12

OMIM

CCDS

HPRD

IMGT

EMBL

AC125372 AC126676 AC140055

GenPept