Version 5.4
Mus musculus Protein: Ift88
Summary
InnateDB Protein IDBP-537388.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ift88
Protein Name intraflagellar transport 88 homolog (Chlamydomonas)
Synonyms AW552028; flexo; fxo; orpk; polaris; Tg737; Tg737Rpw; TgN737Rpw; Ttc10;
Species Mus musculus
Ensembl Protein ENSMUSP00000120286
InnateDB Gene IDBG-168502 (Ift88)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 11 [view]
Protein-Protein 11 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0001654 eye development
GO:0001822 kidney development
GO:0001889 liver development
GO:0003382 epithelial cell morphogenesis
GO:0007219 Notch signaling pathway
GO:0007224 smoothened signaling pathway
GO:0007288 sperm axoneme assembly
GO:0007290 spermatid nucleus elongation
GO:0007368 determination of left/right symmetry
GO:0007399 nervous system development
GO:0007420 brain development
GO:0007507 heart development
GO:0008104 protein localization
GO:0008544 epidermis development
GO:0008589 regulation of smoothened signaling pathway
GO:0009887 organ morphogenesis
GO:0009952 anterior/posterior pattern specification
GO:0009953 dorsal/ventral pattern formation
GO:0021513 spinal cord dorsal/ventral patterning
GO:0021537 telencephalon development
GO:0030324 lung development
GO:0031016 pancreas development
GO:0031122 cytoplasmic microtubule organization
GO:0034405 response to fluid shear stress
GO:0036334 epidermal stem cell homeostasis
GO:0042384 cilium assembly
GO:0042487 regulation of odontogenesis of dentin-containing tooth
GO:0042733 embryonic digit morphogenesis
GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway
GO:0045598 regulation of fat cell differentiation
GO:0048853 forebrain morphogenesis
GO:0050680 negative regulation of epithelial cell proliferation
GO:0055007 cardiac muscle cell differentiation
GO:0060021 palate development
GO:0060122 inner ear receptor stereocilium organization
GO:0060173 limb development
GO:0060271 cilium morphogenesis
GO:0060411 cardiac septum morphogenesis
GO:0060426 lung vasculature development
GO:0060914 heart formation
GO:0070613 regulation of protein processing
GO:0090102 cochlea development
Cellular Component
GO:0002080 acrosomal membrane
GO:0005813 centrosome
GO:0005929 cilium
GO:0005930 axoneme
GO:0030992 intraciliary transport particle B
GO:0031512 motile primary cilium
GO:0032391 photoreceptor connecting cilium
GO:0036064 ciliary basal body
GO:0060091 kinocilium
GO:0097541 axonemal basal plate
GO:0097542 ciliary tip
GO:0097546 ciliary base
Protein Structure and Domains
PDB ID MGI:98715
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL D6RJ41
UniProt Splice Variant
Entrez Gene 21821
UniGene Mm.4653
RefSeq
MGI ID
MGI Symbol Ift88
OMIM
CCDS
HPRD
IMGT
EMBL AC124462 AC154675
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca