InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Rab5c

Summary

InnateDB Protein

IDBP-537405.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Rab5c

Protein Name

RAB5C, member RAS oncogene family

Synonyms

AI326010; Rabl;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000123581

InnateDB Gene

IDBG-211569 (Rab5c)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 24 interaction(s) predicted by orthology.

Experimentally validated
Total	8 [view]
Protein-Protein	8 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	24 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003924	GTPase activity
GO:0005515	protein binding
GO:0005525	GTP binding
GO:0019003	GDP binding

Biological Process

GO:0006184	GTP catabolic process
GO:0007032	endosome organization
GO:0007264	small GTPase mediated signal transduction
GO:0015031	protein transport
GO:0030100	regulation of endocytosis

Cellular Component

GO:0005622	intracellular
GO:0005765	lysosomal membrane
GO:0005811	lipid particle
GO:0030139	endocytic vesicle

Protein Structure and Domains

PDB ID

MGI:105306

InterPro

IPR001806 Small GTPase superfamily
IPR003579 Small GTPase superfamily, Rab type
IPR005225 Small GTP-binding protein domain
IPR013684 Mitochondrial Rho-like
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00071
PF08477

PRINTS

PR00449

PIRSF

SMART

SM00175

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

A2A5F6

UniProt Splice Variant

Entrez Gene

19345

UniGene

Mm.29829

RefSeq

MGI ID

MGI Symbol

Rab5c

OMIM

CCDS

HPRD

IMGT

EMBL

AL591469

GenPept